Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6134447 | Journal of Virological Methods | 2013 | 6 Pages |
Abstract
⺠The haemagglutinin of highly pathogenic avian influenza was cloned into Pichia sp. ⺠The antigen was expressed, purified and the haemagglutination property was analysed. ⺠The recombinant haemagglutinin was found to elicit neutralizing antibodies in mice. ⺠This method of vaccine manufacturing in Pichia pastoris may be cheaper and quicker. ⺠This method will help to produce vaccines against an avian influenza pandemic.
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Authors
Subathra Murugan, Santhakumar Ponsekaran, Lingaraja Kannivel, Lakshmi Narasu Mangamoori, Dev Chandran, Srinivasan Villuppanoor Alwar, Chandrani Chakravarty, Sunil K. Lal,