Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6134459 | Journal of Virological Methods | 2013 | 7 Pages |
Abstract
⺠Two monoclonal antibodies against SARS CoV S1 antigen were generated by hybridomatechnology. ⺠Bispecific antibody (bsmAb) was developed by Quadroma technology. ⺠Mono- and bispecific antibodies were evaluated by sandiwichELISA for immunodiagnosis. ⺠We report that bsmAb-based ELISA is more sensitive than the mAb-based ELISA for detection of the S1 antigen.
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Authors
Hoon H. Sunwoo, Arivazhagan Palaniyappan, Advaita Ganguly, Pravin K. Bhatnagar, Dipankar Das, Ayman O.S. El-Kadi, Mavanur R. Suresh,