Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6134467 | Journal of Virological Methods | 2013 | 9 Pages |
Abstract
⺠A quantitative TaqMan® assay was developed to measure HIV-1 proviral DNA. ⺠The assay has broad specificity as it can detect many HIV-1 subtypes. ⺠The assay is very sensitive as it detects reliably 2 Ã 101 to 2 Ã 107 HIV-1 DNA copies in the presence of background chromosomal DNA. ⺠With different primers sets and a single probe the assay can discriminate between linear and circular HIV-1 DNA forms.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Virology
Authors
Renée M. van der Sluis, Thijs van Montfort, Mireille Centlivre, Nick C.T. Schopman, Marion Cornelissen, Rogier W. Sanders, Ben Berkhout, Rienk E. Jeeninga, William A. Paxton, Georgios Pollakis,