| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6134570 | Journal of Virological Methods | 2013 | 6 Pages |
Abstract
⺠The percentage of mRNA positive samples increases with the severity of the cytological diagnosis, but not in histological diagnosis. ⺠E6/E7 mRNA assay had significant higher positivity rate than the Hybrid Capture 2 assay (75.3% versus 62.3%). ⺠The HPV mRNA assay and the HC2 assay had the same sensitivity of CIN2+. However, the specificity of CIN2+ for the HPV mRNA assay was significantly lower than HC2 assay. ⺠E6/E7 mRNA assay can be used as auxiliary tool to follow up.
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Authors
Yong Shen, Jiaomei Gong, Yanxia He, Guomei Cheng, Paul Okunieff, Xiaofu Li,