Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6134575 | Journal of Virological Methods | 2013 | 10 Pages |
Abstract
⺠The eukaryotic expression plasmids, pBudCE-NS4A and pBudCE-NS4B, were constructed. ⺠Two recombinant vaccinia viruses, rWR-NS4A and rWR-NS4B, were also constructed. ⺠The conditions of the priming-boosting strategy were established in the mouse model. ⺠The IFN-γ response of mice spleen cells was detected using ICS and ELISPOT assays. ⺠Three peptides of NS4A and NS4B protein were identified as H-2Kd restricted CTL epitopes.
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Authors
Weijun Zhang, Xuemei Li, Yan Lin, Donghua Tian,