Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6134689 | Journal of Virological Methods | 2013 | 8 Pages |
Abstract
⺠The G-H loop of type Asia1 FMDV capsid can tolerate peptide insertion. ⺠Three sites of the VP1 were selected for insertion of a foreign epitope. ⺠The type O FMDV neutralising epitope was displayed on the type Asia1 capsid. ⺠The type O epitope induced anti-type O FMDV IgG and neutralising antibodies. ⺠The insertion does not interfere with the immunogenicity of the type Asia1 capsid.
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Authors
Zheng Chai, Haiwei Wang, Guohui Zhou, Decheng Yang, Jingfei Wang, Li Yu,