| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6134746 | Journal of Virological Methods | 2012 | 9 Pages |
Abstract
⺠A convenient proteolytic analysis of HIV protease was created based on a standard ELISA-based system. ⺠Two specific monoclonal antibodies were used for monitoring of the alteration in cleaved matrix-capsid polypeptide. ⺠The influence of various mutations in HIV-PRs isolated from drug-resistant strains could be validated. ⺠The assay provides a high-throughput technique for validating the efficiency and facilitating the discovery of new PIs.
Keywords
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Authors
Kuntida Kitidee, Sawitree Nangola, Sudarat Hadpech, Witida Laopajon, Watchara Kasinrerk, Chatchai Tayapiwatana,