Article ID Journal Published Year Pages File Type
6134828 Journal of Virological Methods 2012 7 Pages PDF
Abstract
► A novel strategy for targeted delivery of human interferon gamma to the HBsAg-secreting hepatocytes mediated by pcDNA3.1 was developed. ► This strategy resulted in robust induction of interferon gamma expression in a cell-specific fashion with a very low background. ► The cell-specific interferon gamma expression controlled effectively HBV replication in HepG2.2.15 cells without cell toxicity.
Related Topics
Life Sciences Immunology and Microbiology Virology
Authors
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