Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6134828 | Journal of Virological Methods | 2012 | 7 Pages |
Abstract
⺠A novel strategy for targeted delivery of human interferon gamma to the HBsAg-secreting hepatocytes mediated by pcDNA3.1 was developed. ⺠This strategy resulted in robust induction of interferon gamma expression in a cell-specific fashion with a very low background. ⺠The cell-specific interferon gamma expression controlled effectively HBV replication in HepG2.2.15 cells without cell toxicity.
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Authors
Quancheng Kan, Duolu Li, Zujiang Yu,