| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6135138 | Journal of Virological Methods | 2012 | 11 Pages |
Abstract
⺠A system for producing a recombinant HSV-1 expressing exogenous epitopes was created. ⺠Traffic-light inspired fluorescent markers gauged the purity of recombinant viruses. ⺠Adaptability was demonstrated by generating recombinants for 3 immunologic epitopes. ⺠Recombinants were rapidly identified and isolated to purity via stoplight indicators. ⺠Presentation of a CD8 epitope was quantified using a T cell hybridoma reporter cell.
Related Topics
Life Sciences
Immunology and Microbiology
Virology
Authors
Rebecca L. Sanchez, Alistair J. Ramsay, Timothy P. Foster,