Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6135714 | Microbes and Infection | 2014 | 6 Pages |
Abstract
Immunity against Brucella abortus depends on the recognition of pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors (PRRs). Signaling pathways triggered by Brucella DNA involves TLR9, AIM2 and possibly STING and MAVS. Herein, we review the advances in B. abortus DNA sensing by host innate immune receptors and the progress in this field.
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Authors
Priscila Carneiro Campos, Marco Túlio Ribeiro Gomes, Gabriela Guimarães, Miriam Maria Silva Costa Franco, Fernanda Martins Marim, Sergio Costa Oliveira,