Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6135924 | Microbes and Infection | 2011 | 6 Pages |
Abstract
Unprotected sexual intercourse between discordant couples is by far the most frequent mode of HIV-1 (human immunodeficiency virus type 1) transmission being semen the main vector for HIV-1 dissemination worldwide. Semen is usually considered merely as a vehicle for HIV-1 transmission. In this review we discuss recent observations suggesting that beyond being a carrier for virus particles semen markedly influences the early events involved in sexual transmission of HIV through the mucosal barriers.
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Authors
Juan Sabatté, Federico Remes Lenicov, Mercedes Cabrini, Christian Rodriguez Rodrigues, MatÃas Ostrowski, Ana Ceballos, Sebastián Amigorena, Jorge Geffner,