Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6135959 | Microbes and Infection | 2012 | 7 Pages |
Abstract
T helper (Th) 1 and 17 cells play important roles in host protective responses against tuberculosis. Early Secretory Antigenic Target 6; a Region of Difference 1 (RD1) encoded protein, mounts Th17-responses in the lung. Therefore, lack of RD-1 region makes Bacillus Calmette-Guérin (BCG) less vaccine efficacious than parent strains.
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Authors
Ramesh Chandra Rai, Ved Prakash Dwivedi, Samit Chatterjee, Durbaka Vijaya Raghava Prasad, Gobardhan Das,