Article ID Journal Published Year Pages File Type
6135959 Microbes and Infection 2012 7 Pages PDF
Abstract
T helper (Th) 1 and 17 cells play important roles in host protective responses against tuberculosis. Early Secretory Antigenic Target 6; a Region of Difference 1 (RD1) encoded protein, mounts Th17-responses in the lung. Therefore, lack of RD-1 region makes Bacillus Calmette-Guérin (BCG) less vaccine efficacious than parent strains.
Related Topics
Life Sciences Immunology and Microbiology Immunology
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