Article ID Journal Published Year Pages File Type
6136006 Microbes and Infection 2012 5 Pages PDF
Abstract

Airway epithelial cells are the main cells infected by respiratory viruses including rhinoviruses and respiratory syncytial virus. Virus modulation of inhibitory molecule PD-L1 on epithelial cells may be important in limiting anti-viral effector CD8+ T cell responses and, consequently, worsening acute virus-induced lung tissue damage.

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Related Topics
Life Sciences Immunology and Microbiology Immunology
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Role of PD-L1/PD-1 in the immune response to respiratory viral infections
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