| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6136017 | Microbes and Infection | 2011 | 9 Pages |
Abstract
Brucella can parasitize within human antigen-presenting cells modifying phagocytosis, phagolysosome fusion, antigen presentation, cytokine secretion, and apoptosis. Subversion of innate immune mechanisms by Brucella leads to defective Th1 immune responses and T-cell anergy in chronic brucellosis patients. This review summarizes the cellular immune responses in brucellosis, based on data derived exclusively from human cells or cell lines.
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Authors
Panagiotis Skendros, Georgios Pappas, Panagiota Boura,