Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6136027 | Microbes and Infection | 2011 | 7 Pages |
Abstract
The deubiquitinating enzyme A20 (also known as TNFAIP3) is essential for maintaining immune homeostasis. A20 is a key regulator of inflammatory, antiviral and apoptotic signaling pathways. Here, we review recent advances illustrating the role of A20 as an essential negative regulator of inflammatory and antiviral signaling.
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Authors
Kislay Parvatiyar, Edward W. Harhaj,