Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6137078 | Parasitology International | 2012 | 8 Pages |
Abstract
⺠We predicted six promiscuous Th cell epitopes using immunoinformatics method. ⺠All six sequences predicted can be expressed in normal day 3 schistosomula. ⺠Four of six peptides could bind to both I-Ad and I-Ed molecules of the mice. ⺠Three of the six predicted peptides could induce a recall CD4+ Th1 response in vitro. ⺠We provided a novel method for the discovery of Th epitopes against schistosoma.
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Authors
Yan Li Zhang, Kan Jia, Ben Peng Zhao, Ying Li, Chun Xiu Yuan, Jian Mei Yang, Jiao Jiao Lin, Xin Gang Feng,