Article ID Journal Published Year Pages File Type
6137078 Parasitology International 2012 8 Pages PDF
Abstract
► We predicted six promiscuous Th cell epitopes using immunoinformatics method. ► All six sequences predicted can be expressed in normal day 3 schistosomula. ► Four of six peptides could bind to both I-Ad and I-Ed molecules of the mice. ► Three of the six predicted peptides could induce a recall CD4+ Th1 response in vitro. ► We provided a novel method for the discovery of Th epitopes against schistosoma.
Related Topics
Life Sciences Immunology and Microbiology Parasitology
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