Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6138187 | Trends in Parasitology | 2014 | 14 Pages |
Abstract
Evidence-informed health policy making is reliant on systematic access to, and appraisal of, the best available research evidence. This review suggests a strategy to improve the speed at which evidence is gathered on new vector control tools (VCTs) using a framework based on measurements of the vectorial capacity of an insect population to transmit disease. We explore links between indicators of VCT efficacy measurable in small-scale experiments that are relevant to entomological and epidemiological parameters measurable only in large-scale proof-of-concept randomised control trials (RCTs). We hypothesise that once RCTs establish links between entomological and epidemiological indicators then rapid evaluation of new products within the same product category may be conducted through smaller scale experiments without repetition of lengthy and expensive RCTs.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Parasitology
Authors
John Vontas, Sarah Moore, Immo Kleinschmidt, Hilary Ranson, Steve Lindsay, Christian Lengeler, Nicholas Hamon, Tom McLean, Janet Hemingway,