Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6138922 | Virology | 2015 | 9 Pages |
Abstract
Adenoviruses are a ubiquitous group of viruses that have been found in a wide range of hosts. A novel adenovirus from a skunk suffering from acute hepatitis was isolated and its DNA genome sequenced. The analysis revealed this virus to be a new member of the genus Mastadenovirus, with a genome of 31,848Â bp in length containing 30 genes predicted to encode proteins, and with a G+C content of 49.0%. Global genomic organization indicated SkAdV-1 was similar in organization to bat and canine adenoviruses, and phylogenetic comparison suggested these viruses shared a common ancestor. SkAdV-1 demonstrated an ability to replicate in several mammalian liver cell lines suggesting a potential tropism for this virus.
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Immunology and Microbiology
Virology
Authors
Robert A. Kozak, James G. Ackford, Patrick Slaine, Aimin Li, Susy Carman, Doug Campbell, M. Katherine Welch, Andrew M. Kropinski, Ãva Nagy,