| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6141051 | Virology | 2013 | 11 Pages |
Abstract
⺠We previously identified HSP90AB1 as a host factor essential for HIV replication. ⺠HSP90AB1 expression rescued infectivity of HIV with incomplete CA-SP1 cleavage. ⺠Here we show that HSP90AB1 can also rescue HIV with defective cores. ⺠HSP90AB1 expression increases with hyperthermia. ⺠Hyperthermia increased HIV infectivity up to 30-fold and rescued CA-mutant virus.
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Authors
Pheroze Joshi, Barbara Sloan, Bruce E. Torbett, Cheryl A. Stoddart,