| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6141061 | Virology | 2013 | 11 Pages |
Abstract
⺠Canine distemper virus (CDV) was shown to use dog nectin-4 as a receptor. ⺠Two splice variants of dog nectin-4 were identified. ⺠Both dog nectin-4 and human nectin-4 could function as an entry factor for CDV. ⺠CDV infection could be inhibited by RNAi or with nectin-4 antibodies. ⺠Dog nectin-4 promotes syncytia formation, which could be inhibited by siRNA treatment.
Related Topics
Life Sciences
Immunology and Microbiology
Virology
Authors
Ryan S. Noyce, Sebastien Delpeut, Christopher D. Richardson,