Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6141143 | Virology | 2012 | 7 Pages |
Abstract
⺠We examined the effect of HPV16 E7 on mitotic checkpoint activity. ⺠E7 inhibited cyclin B degradation. ⺠Multiple E7 domains contribute to this activity. ⺠Inhibition of cyclin B degradation reflects spindle assembly checkpoint engagement. ⺠Spindle assembly checkpoint activation in response to microtubule poisons is normal.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Virology
Authors
Yueyang Yu, Karl Munger,