Article ID Journal Published Year Pages File Type
6141143 Virology 2012 7 Pages PDF
Abstract
► We examined the effect of HPV16 E7 on mitotic checkpoint activity. ► E7 inhibited cyclin B degradation. ► Multiple E7 domains contribute to this activity. ► Inhibition of cyclin B degradation reflects spindle assembly checkpoint engagement. ► Spindle assembly checkpoint activation in response to microtubule poisons is normal.
Related Topics
Life Sciences Immunology and Microbiology Virology
Authors
, ,