| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6142175 | Virus Research | 2015 | 9 Pages |
Abstract
Parkinson's disease is one of several neurodegenerative diseases associated with a misfolded, aggregated and pathological protein. In Parkinson's disease this protein is alpha-synuclein and its neuronal deposits in the form of Lewy bodies are considered a hallmark of the disease. In this review we describe the clinical and experimental data that have led to think of alpha-synuclein as a prion-like protein and we summarize data from in vitro, cellular and animal models supporting this view.
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Authors
Maria Eugenia Herva, Maria Grazia Spillantini,