Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6142297 | Virus Research | 2014 | 10 Pages |
Abstract
In this review, we summarize our current understanding of SARS-CoV enzymes involved in RNA biochemistry, such as the in vitro characterization of a highly active and processive RNA polymerase complex which can associate with methyltransferase and 3â²-5â² exoribonuclease activities involved in RNA capping, and RNA proofreading, respectively. The recent discoveries reveal fascinating RNA-synthesizing machinery, highlighting the unique position of coronaviruses in the RNA virus world.
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Authors
Marion Sevajol, Lorenzo Subissi, Etienne Decroly, Bruno Canard, Isabelle Imbert,