Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6142770 | Virus Research | 2013 | 4 Pages |
Abstract
Recently, a novel bunyavirus, severe fever with thrombocytopenia syndrome virus (SFTSV), was isolated in central China. The virus can cause multi-clinical symptoms: severe fever, thrombocytopenia, leukocytopenia, with a mortality rate of â¼10%. Several studies show that SFTSV could undergo rapid evolution via gene mutation and homologous recombination. However, as an important evolutionary force for segmented-genome viruses, reassortment has not been reported in SFTSV. In this study, we identified two SFTSV strains of which the S segment has different origin from M and L, suggesting that reassortment might be potential force driving rapid change of SFTSV. This result might shed new light on the evolutionary behavior of the novel virus.
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Authors
Nai-Zheng Ding, Zhi-Fei Luo, Dan-Dan Niu, Wei Ji, Xiu-Han Kang, Si-Si Cai, Dong-Shuai Xu, Qiu-Wen Wang, Cheng-Qiang He,