Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6142814 | Virus Research | 2012 | 6 Pages |
Abstract
⺠MPL inhibited the secretions of HBsAg and HBeAg in HepG2.2.15 at low concentration. ⺠MPL steadily suppressed HBV DNA and HBV cccDNA levels. ⺠MPL could up-regulate the mRNA expression of IL-2, INF-γ and MxA. ⺠MPL enhanced immune response to inhibit HBV by activating NF-κB p65 signal pathway.
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Authors
Xiaohong Cao, Minghui Zhou, Songxue Wang, Chunling Wang, Lihua Hou, Yiqing Luo, Linye Chen,