Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6142872 | Virus Research | 2013 | 10 Pages |
Abstract
⺠Ribavirin effectively inhibited porcine nidovirus infection in a dose-dependent manner. ⺠Ribavirin affected post-entry steps of the replication cycle of PRRSV and PEDV. ⺠GTP depletion may be essential for the ribavirin activity against porcine nidoviruses. ⺠Ribavirin did not trigger catastrophic mutations in the nidoviral genome. ⺠Treatment of ribavirin could be a good antiviral therapy against porcine nidoviruses.
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Authors
Youngnam Kim, Changhee Lee,