Article ID Journal Published Year Pages File Type
6143060 Virus Research 2012 11 Pages PDF
Abstract
► We construct two epitope-based proteins (Cp1/Cp2) as subunit vaccine of PRRSV. ► We use the N terminal 22-370 aa of porcine gp96 (Gp96N) as the adjuvant. ► Gp96N can enhance humoral and cellular immunity elicited by Cp1/Cp2. ► Gp96N could improve innate and adaptive immunity with Th1 biased immune response.
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Life Sciences Immunology and Microbiology Virology
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Gp96 enhances the immunogenicity of subunit vaccine of porcine reproductive and respiratory syndrome virus
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