| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6143078 | Virus Research | 2012 | 7 Pages |
Abstract
⺠We identify the region of aa 65-107 of nsp10 as the interaction domain with nsp16 in vivo. ⺠We identify the region of aa 42-120 of nsp10 as the functional domain for activating nsp16 in vitro. ⺠We design and synthesize two inhibitory peptides K12 and K29 that could inhibit the MTase activity of nsp10/nsp16 complex.
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Related Topics
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Immunology and Microbiology
Virology
Authors
Min Ke, Yu Chen, Andong Wu, Ying Sun, Ceyang Su, Hao Wu, Xu Jin, Jiali Tao, Yi Wang, Xiao Ma, Ji-An Pan, Deyin Guo,