| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6143098 | Virus Research | 2012 | 10 Pages |
Abstract
⺠RSV vaccine MEDI-559 has 39 nt silent differences compared to a previous candidate. ⺠Variants of temperature-sensitive (ts) MEDI-559 can occur at elevated temperatures. ⺠Most variants involved changes at one or two ts markers called 248 and 1030. ⺠One variant maintained all ts and cp markers and had 2 novel changes in polymerase. ⺠All variants were highly attenuated in cotton rats.
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Authors
Jeanne H. Schickli, Jasmine Kaur, Roderick S. Tang,