Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6143172 | Virus Research | 2012 | 10 Pages |
Abstract
⺠A vCPXVÎCP77 mutant was constructed by bacterial artificial chromosome mutagenesis. ⺠Integrity and functionality of the vCPXVÎCP77 mutant were confirmed. ⺠Host restriction of vCPXVÎCP77 in CHO cells could be complemented by expression of CP77. ⺠No other cell type or species origin mediating a CP77 dependent host range effect could be identified. ⺠The vCPXVÎCP77 mutant can be applied to determine additional functions of CP77.
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Authors
Livia Schuenadel, B. Karsten Tischer, Andreas Nitsche,