Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6143190 | Virus Research | 2012 | 6 Pages |
Abstract
⺠CHO cell-adapted strains of HEV71 sub-genogroups B5 and C2 were isolated. ⺠HEV71 sub-genogroup C4 failed to adapt to CHO cells during serial passage. ⺠CHO cell-adapted HEV71 has amino acid mutation at position 149 of the VP2 gene. ⺠HEV71-C4 constructed to contain mutation VP2-K149 â I or M can grow in CHO cells.
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Authors
Zainun Zaini, Patchara Phuektes, Peter McMinn,