Article ID Journal Published Year Pages File Type
6143191 Virus Research 2012 13 Pages PDF
Abstract
► Multiple positive and negative control elements are present in the ORF46 promoter. ► Activation of the ORF46 promoter by ORF50 protein is mediated through RBP-Jκ. ► The negative elements in the ORF46 promoter suppress ORF50 responsiveness. ► The negative region of the ORF46 promoter contains Sp1-binding sequences. ► Sodium butyrate can relieve the negative regulation of the ORF46 promoter.
Related Topics
Life Sciences Immunology and Microbiology Virology
Authors
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