| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6143241 | Virus Research | 2012 | 10 Pages |
Abstract
⺠A panel of recombinant human antibodies to orthopoxviruses was developed. ⺠Seven phage-displaying scFvs neutralized CPXV and VACV in PRNT. ⺠Five phage-displaying scFvs neutralize Monkeypox virus (MPXV) in PRNT. ⺠Neutralizing antibodies recognized recombinant J3L protein in Western blot analysis. ⺠Fully human neutralizing mAb displayed Kd of 0.7 nM.
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Authors
Nina Tikunova, Viktoriya Dubrovskaya, Vera Morozova, Tatiana Yun, Yana Khlusevich, Nikolai Bormotov, Aleksandr Laman, Fedor Brovko, Aleksandr Shvalov, Eugeni Belanov,