Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6143553 | Virus Research | 2011 | 4 Pages |
Abstract
One year after the emergence of the 2009 influenza (H1N1) pandemic, most cases have been relatively mild; however, the possibility of enhanced viral growth ability by reassortment with seasonal viruses cannot be overlooked. Here, we show that reassortant viruses containing a seasonal H1 HA and swine-origin NA and M genes have enhanced virus growth over their wild-type parental viruses. The emergence of such viruses in nature could, therefore, represent a threat.
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Authors
Cássio Pontes Octaviani, Chengjun Li, Takeshi Noda, Yoshihiro Kawaoka,