Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6145324 | American Journal of Obstetrics and Gynecology | 2015 | 7 Pages |
Abstract
LIP localized within the uterus and did not cross the placenta to the fetus. IND within the fetus was reduced 7.6-fold while encapsulated within the LIP and the pharmacologic effects of IND were maintained. Thus, LIP provide a novel therapeutic approach to correct the primary clinical limitation of IND by reducing placental passage to the fetus.
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Authors
Jerrie S. MD, Jenolyn F. MSc, Fransisca PhD, Mateo MD, Monica MD, PhD, Biana MScPharm, PhD,