Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6145345 | American Journal of Obstetrics and Gynecology | 2015 | 9 Pages |
Abstract
Among the 4 genes that were studied, fetal membranes from PTB demonstrate differences in OXTR methylation and regulation and expression, which suggest that epigenetic alteration of this gene in fetal membrane may likely be indicating an in utero programing of this gene and serve as a surrogate in a subset of PTB. The usefulness of OXTR hypermethylation as a surrogate for a link to ASD should be further evaluated in longitudinal and in vitro studies.
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Authors
Fara MD, Sasha E. BS, Talar MS, Huaizhi MS, Eryn H. DO, George R. MD, Alicia K. PhD, Ramkumar MS, PhD,