Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6145386 | American Journal of Obstetrics and Gynecology | 2014 | 7 Pages |
Abstract
In PCOS, increased cytokine release from MNCs following LPS exposure in the fasting state reveals the presence of MNC preactivation. Importantly, this phenomenon is independent of obesity and may contribute to the development of insulin resistance and hyperandrogenism in PCOS. In contrast, the source of plasma IL-6 elevations in PCOS may be excess adiposity.
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Authors
Frank MD, John P. PhD, Neal S. PhD, Judi BS,