Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6151540 | Contemporary Clinical Trials | 2009 | 5 Pages |
Abstract
The recurrence free survival is not a good surrogate for overall survival in clinical trials with non significant treatment effects and moderate for significant treatment effects. This shows that the level of significance of treatment effect should be taken into account in validation process of surrogate endpoints.
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Authors
Y. Sertdemir, R. Burgut,