| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6151837 | Journal of the Chinese Medical Association | 2015 | 8 Pages |
Abstract
The conditional medium of iPSCs contains plenty of cytoprotective, immune-modulative and rescue chemicals, contributing to the maintenance of neuronal function and retinal layers in light-damaged retina compared with apoptotic iPSC-CM and PBS. The antiapoptotic effect of iPSC-CM also shows promise in restoring damaged neurons. This result demonstrates that iPSC-CM may serve as an alternative to cell therapy alone to treat retinal light damage and maintain functional and structural integrity of the retina.
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Authors
Hua-Ming Chang, Kuo-Hsuan Hung, Chih-Chien Hsu, Tai-Chi Lin, Szu-Yu Chen,