Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6155777 | Seminars in Perinatology | 2015 | 14 Pages |
Abstract
Sickle cell disease is a group of disorders, the majority of which are detected through state newborn screening programs. There is limited knowledge of disease prevalence in the U.S. population. We report 20 years of case finding and laboratory data for sickle cell disease and trait to assist in: planning for health services delivery; providing data for researchers; aiding in tracking health outcome trends; and assessing sickle gene prevalence in the newborn population. During the 20-year period, there were 39,422 confirmed cases of sickle cell disease among 76,527,627 newborn births screened (1:1941) and 1,107,875 laboratory reports of probable sickle trait among 73,951,175 newborn births screened (1:67). The highest sickle cell disease incidence during the 20 years was in the District of Columbia (1:437) followed by Mississippi (1:683) and South Carolina (1:771). For sickle cell trait, the highest incidences were in the District of Columbia (1:22), Mississippi (1:26), and South Carolina (1:31).
Related Topics
Health Sciences
Medicine and Dentistry
Medicine and Dentistry (General)
Authors
Bradford L. PhD, Michele A. MD, PhD, James R. MD, Marie Y. MD, MPH,