Article ID Journal Published Year Pages File Type
6156961 American Journal of Kidney Diseases 2015 10 Pages PDF
Abstract
Drug effects on serum PTH, phosphorus, and calcium levels are weakly and imprecisely correlated with all-cause and cardiovascular death in the setting of CKD. Risks of mortality (patient-level outcome) cannot be inferred from treatment-induced changes in biochemical outcomes in people with CKD. Similarly, existing data do not exclude a mortality benefit with treatment. Trials need to address patient-centered outcomes to evaluate drug effectiveness in this setting.
Related Topics
Health Sciences Medicine and Dentistry Nephrology
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