Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6156961 | American Journal of Kidney Diseases | 2015 | 10 Pages |
Abstract
Drug effects on serum PTH, phosphorus, and calcium levels are weakly and imprecisely correlated with all-cause and cardiovascular death in the setting of CKD. Risks of mortality (patient-level outcome) cannot be inferred from treatment-induced changes in biochemical outcomes in people with CKD. Similarly, existing data do not exclude a mortality benefit with treatment. Trials need to address patient-centered outcomes to evaluate drug effectiveness in this setting.
Keywords
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Authors
Suetonia C. MBChB, PhD, Armando PhD, Valeria MSc, Jonathan C. MBChB, PhD, Petra PhD, Marcello MD, Giorgia MSc, Marinella MSc, Giovanni F.M. MD, PhD,