| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6158203 | American Journal of Kidney Diseases | 2010 | 10 Pages |
Abstract
Our results suggest a profibrotic imbalance in the TGF-β-SMAD-CTGF axis in NSF skin lesions. Significantly increased dermal expression of TGF-β and TIMP-1 in non-NSF hemodialysis patients in comparison to healthy participants emphasizes the need for a hemodialysis control group for future investigations and suggests a pre-existing profibrotic situation in the skin of hemodialysis patients.
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Authors
Gisela MD, Thilo MD, Marina Skrygan, Björn Burkert, Peter MD, Lars Christian MD, Alexander MD,