Loss of Heterozygosity Analysis at Different Chromosome Regions in Wilms Tumor Confirms 1p Allelic Loss as a Marker of Worse Prognosis: A Study from the Italian Association of Pediatric Hematology and Oncology

Article ID	Journal	Published Year	Pages	File Type
6159169	The Journal of Urology	2013	8 Pages	PDF

Abstract

Chromosome 1p loss of heterozygosity seems to be a risk factor for nonanaplastic Wilms tumor, possibly regardless of other clinical factors. Our findings were uninformative regarding loss of heterozygosity in the other chromosomal regions tested.

Keywords

DFS AIEOP loss of heterozygosity disease-free survival overall survival Wilms tumor Dactinomycin Doxorubicin LOH Kidney neoplasms vincristine Pediatrics

Related Topics

Health Sciences Medicine and Dentistry Nephrology

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Loss of Heterozygosity Analysis at Different Chromosome Regions in Wilms Tumor Confirms 1p Allelic Loss as a Marker of Worse Prognosis: A Study from the Italian Association of Pediatric Hematology and Oncology

Authors

Filippo Spreafico, Beatrice Gamba, Luigi Mariani, Paola Collini, Paolo D'Angelo, Andrea Pession, Andrea Di Cataldo, Paolo Indolfi, Marilina Nantron, Monica Terenziani, Carlo Morosi, Paolo Radice, Daniela Perotti,