Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6159552 | The Journal of Urology | 2011 | 8 Pages |
Abstract
Several promising predictive parameters are currently available to distinguish benign from malignant pheochromocytoma. Large (5 cm or greater) or heavy (250 gm or greater) tumors, multifocal and extra-adrenal tumors, early onset postoperative hypertension and higher plasma or urine metadrenaline are high risk factors predictive of malignant pheochromocytoma. Also, expression of the 3 angiogenesis or metastasis related genes VEGF, Cox-2 and MVD helps determine the diagnosis of malignancy and suggests strict followup.
Keywords
fluorodeoxyglucosePCCMVDNMNSDHFDGCOX-2CSIMRIGene expressionMicrovessel densityDiagnosisChemical shift imagingMagnetic resonance imagingposition emission tomographycomputerized tomographyDifferentialsuccinate dehydrogenaseCyclooxygenase-2Adrenal glandsPheochromocytomaVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)MIBGmetanephrinenormetanephrinePET
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Authors
Feng Feng, Yu Zhu, XiaoJing Wang, YuXuan Wu, WenLong Zhou, XiaoLong Jin, RongMing Zhang, FuKang Sun, Zacharia Kasoma, ZhouJun Shen,