Importance of Methodology on 99mTechnetium Dimercapto-Succinic Acid Scintigraphic Image Quality: Imaging Pilot Study for RIVUR (Randomized Intervention for Children With Vesicoureteral Reflux) Multicenter Investigation

Methodology and image quality for 99mtechnetium dimercapto-succinic acid scintigraphy varied more than expected between institutions. The most common reason for poor image quality was inadequate count acquisition with insufficient attention to the tradeoff between administered dose, length of image acquisition, start time of imaging and resulting image quality. Inter-observer core reader agreement was high. The pilot study ensured good diagnostic quality standardized images for the Randomized Intervention for Children With Vesicoureteral Reflux investigation.