| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6162150 | Kidney International | 2013 | 4 Pages |
Abstract
Proton pump inhibitors (PPIs) promote hypomagnesemia through loss of active Mg2+ absorption via transient receptor potential melastatin-6 and -7 (TRPM6/7). Danziger et al. confirm the association of PPIs with hypomagnesemia in patients hospitalized at a tertiary medical center. They found that patients taking PPIs, compared with those receiving histamine-2 antagonists or no acid-suppressive medications, had a decline in serum Mg2+ after adjusting for several clinical and laboratory factors. The effect was seen only in those concomitantly receiving diuretics.
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Authors
Mark A. Perazella,