| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6165997 | Urology | 2016 | 8 Pages |
Abstract
Tuberous sclerosis complex (TSC) is a rare autosomal dominant genetic disorder characterized by the development of numerous benign tumors that occur in multiple organ systems throughout the lifetime of the affected individuals. Renal angiomyolipomas occur in up to 80% of TSC patients, and chronic kidney disease from increasing tumor burden is the primary cause of TSC-related mortality. Our review evaluates evidence for localized and systemic therapy in the management of TSC-angiomyolipomas. Urologists or nephrologists experienced in TSC disease should coordinate the care of TSC patients with renal involvement to improve care and reduce costs.
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Authors
Anil Kapoor, Louis Girard, Jean-Baptiste Lattouf, York Pei, Ricardo Rendon, Paul Card, Alan So,