Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6166222 | Urology | 2014 | 7 Pages |
Abstract
The LCS rats had salient characteristics of severe infra-sacral neuropathic bladder dysfunction. TAM and DIS decreased postvoid residual urine volume, but this decrease was not accompanied by an increased Pmax or increased voided volume. Rather, decreased MCC was a possible contributing factor. Moreover, increased nonvoiding contractions after administration of DIS might participate in the decreased MCC. This novel model will be useful in studying the pharmacotherapy of the underactive bladder.
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Authors
Noritoshi Sekido, Jun Kida, Daisuke Wakamatsu, Hiroki Okada, Hidekazu Matsuya,