Impact of Disease Burden on Cryoablation Prostate-specific Antigen Outcomes

Favorable PSA outcomes after primary prostate cryoablation appear to be correlated with disease burden. The relative disease burden as defined by the number of and percent core positive, and the ratio of number of cores positive to prostate gland volume (cm3) are highly prognostic for initial post-cryoablation PSA <0.6 ng/mL, which is associated with favorable long-term biochemical disease-free survival regardless of risk stratification.