Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6172085 | Early Human Development | 2012 | 4 Pages |
Abstract
Using non-invasive fetal magnetoencephalography (fMEG), we investigated spontaneous brain activity in 28 fetuses diagnosed with intrauterine growth restriction (IUGR) and compared the results to 47 normal-growth fetuses. The fetal gestational age ranged from 28 to 39Â weeks with post-natal recordings obtained on 17 of the IUGR fetuses. Power spectrum was computed and was divided into four frequency bands. A significant difference in the relative spectral power in delta, theta and beta bands (PÂ <Â 0.01) was observed only in the 28-32Â week gestation age group with alpha band showing a similar trend (PÂ =Â 0.054). This observation suggests that growth restriction may have a more pronounced effect on the fetal brain in early gestation. Larger population studies could reveal the potential value of fMEG as an additional surveillance tool for growth-restricted fetuses.
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Authors
Hari Eswaran, Rathinaswamy B. Govindan, Naim I. Haddad, Eric R. Siegel, Hubert T. Preissl, Pamela Murphy, Curtis L. Lowery,